Features
- Cover Type: Hard Cover with 384 pages
- Published by: CRC
- Edition: 2nd Edition April 5, 2007
- Written in: English
- ISBN 10 Number: 0849395348
- ISBN 13 Number: 978-0849395345
-
Book Dimensions:
9.3 x 6.2 x 1 inches
- Weighs: 1.4 pounds
Product Review
“… is composed of 17 chapters and provides useful information regarding the selection of an appropriate diabetic model anima. The book lists various types of diabetic models and covers the major models of type-1 and type-2 diabetes. … each chapter includes a description of the model animal’s history of establishment. The chapters also provide the genomic background, biological characteristics, mechanisms of incidence, pathogenesis of complications, and availability of each model animal. These descriptions are based on experimental evidence, and include numerous citations of up-to-date references. The number of tables and diagrams is adequate … source of histopathological information on diabetic model animals. … this book is valuable as a general reference of researchers hesitant about the selection of diabetic model animals for experiments. Overall, this book is a good guide when selecting diabetic model animals. I recommend those veterinary pathologists read this book before beginning experimentsusing diabetic model animals.”
— Akira Yabuki, Laboratory of Veterinary Anatomy, Kagoshima University, Japan, in
Veterinary Pathology, 2007
Product Description
As the incidence of diabetes increases worldwide, the need for recommendations on how to prevent and treat the condition grows exponentially, and so does the need for an authoritative source for information on the appropriate models to study the condition. The new edition of
Animal Models of Diabetes is that source. The book presents updated and expanded information regarding the use of models in experiments with both Type 1 and Type 2 diabetes.
The new edition compiles relevant time-saving information on well-recognized models, including various mice, rats, minipigs, and Rhesus monkeys, and provides extensive references for more in-depth study. It contains new and updated referenced reviews on animals with induced obesity as well as observations on retinopathy in spontaneous diabetes resembling human lesions. The book discusses nutritionally diabetes-prone animals and considerations of insulin resistance and obesity. The contributors also address the importance of recent findings on the pathogenesis of diabetes and its complications in relation to human disease.
Including contributions from prominent experts in the field, the book brings together scattered data and lucidly presents it. This promotes the understanding of the etiopathology of diabetes and offers a new grasp of the insulin action, its negative feedback leading to insulin resistance, and its detrimental outcomes. The book also includes new knowledge on specific complications of diabetes, offering an incentive to test advanced modalities to prevent and inhibit their occurrence.
Search for books at
