The Regulatory Genome: Gene Regulatory Networks In Development...

Features

• Cover Type: Hard Cover with 304 pages
• Published by: Academic Press
• Edition: 1st Edition May 30, 2006
• Written in: English
• ISBN 10 Number: 0120885638
• ISBN 13 Number: 978-0120885633
• Book Dimensions: 9.3 x 7.6 x 0.7 inches
• Weighs: 1.7 pounds

Product Review
"offers evo-devo aficionados an intellectual masterpiece to praiseimpossible to ignorea cornerstone for the comparative analysis of gene regulatory networks"
Detlev Arendt, Developmental Biology Programme, European Molecular Biology Laboratory, Germany in SCIENCE

"a highly informative book, provocative in the best sense of the wordI recommend it highly to anyone interested in the subject."
- Igor B. Dawid, Laboratory of Molecular Genetics, National Institute of Child Health and
Human Development, NIH, in THE FASEB JOURNAL

"Davidson does an great job of reducing the complexity of different developmental pathways and modes of embryonic development in diverse animal phyla."
- Michael Karin, University of California San Diego School of Medicine, in NATURE


"reading this book is a pleasure as it allows us to touch the incredible spirit of a very tough scientista real paradigm."
- Nori Satoh, Department of Zoology, Kyoto University, Japan, in NATURE GENETICS

"Prof. Davidson achieves a remarkable synthesis of key concepts in genomics, embryology, and evolutionary biology."
- Mike Levine, University of California, Berkeley, U.S.A.

"This is a milestone work that requirements to be read by every biologist"
Lee Hood, Institute for Systems Biology,
Seattle, WA, U.S.A.

"Davidson's book is tightly written with an impressive coverage of the field."
Douglas H. Erwin, National Museum of Natural History, Washington D.C., U.S.A.

Product Description
Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology.

The Regulatory Genome gorgeously explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market.

* The only book in the market that is solely devoted to the genomic regulatory code for animal development
* Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding
* Presents a comprehensive treatment of molecular control elements that determine the function of genes
* Provides a comparative treatment of development, based on principles rather than description of developmental processes
* Considers the evolutionary processes in terms of the structural properties of gene regulatory networks
* Includes 42 full-color descriptive figures and diagrams

Reader Reviews
This book will be a revelation to any biologist who has not been reading the literature on development and embryology attentively. Davidson eloquently articulates a real theory of the mechanism by which the genome computes the embryologic development of bilaterian animals. The argument is carefully developed from simple principles to more complex implications. The figures are a major part of the book's exposition, and repay very careful reading of the legends along with the associated text. The references are as current as 2006, so the book is quite cutting edge in its outlook. I heartily recommend it to any biologically sophisticated reader. It does presume elementary knowledge about biochemistry and molecular biology at about the freshman/sophomore college level. Enjoy! Comment | | (Report this)