Genotype - Proteotype - Phenotype Relationships in...

Features

• Cover Type: Hard Cover with 166 pages
• Published by: Springer
• Edition: 1st Edition May 31, 2005
• Written in: English
• ISBN 10 Number: 3540248358
• ISBN 13 Number: 978-3540248354
• Book Dimensions: 9.4 x 6.2 x 0.5 inches
• Weighs: 12.8 ounces

Product Description


Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Genotype-Proteotype-Phenotype relationships. Experts from international laboratories contributed to the  current volume to produce a comprehensive overview of the role of protein misfolding in neurodegeneration. Links between genotype and protein characteristics and between proteotype and clinical phenomenology were discussed across diseases categories. Progress in understanding the role of abnormalities of protein metabolism may lead to the identification of biological markers relevant to disease monitoring and to the development of new therapeutic agents capable of modifying and ameliorating basic neurodegenerative mechanisms.

Reader Reviews
This is an up-to-date review of research in the area of genetics and clinical phenotypes in neurodegenerative diseases, particularly, in ALzheimer's disease. the book provides the newest information and insights into the disease heredity and mechanism and proposes search for new treatments. Very enlightening!