Computer Techniques in Preclinical and Clinical Drug Development

Features

• Cover Type: Hard Cover with 256 pages
• Published by: Informa HealthCare
• Edition: 1st Edition July 23, 1996
• Written in: English
• ISBN 10 Number: 0849376823
• ISBN 13 Number: 978-0849376825
• Book Dimensions: 9.7 x 6.2 x 0.7 inches
• Weighs: 1.2 pounds

Product Description
It is estimated that eighty to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.