Features
- Cover Type: Hard Cover with 632 pages
- Published by: Springer
- Edition: 1st Edition January 31, 2003
- Written in: English
- ISBN 10 Number: 0306474158
- ISBN 13 Number: 978-0306474156
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Book Dimensions:
10.4 x 6.8 x 1.7 inches
- Weighs: 3 pounds
Product Description
This volume foxuses on the status of Ca
2+ ions in regulation of phototransduction, light adaptation and the recovery phase in vertebrate photoreceptors. Particular emphasis is given to Ca
2+-binding proteins and their targets, among them particulate guanylate cyclases, GPCR-coupled kinases and cyclic nucleotide-gated cation channels. The book also expands our understanding of events invovling Ca
2+ in the retinal pigment epithelium, in synaptic transmission and secondary retinal neurons. A significant part of the book is dedicated to the role of Ca
2+ in invertebrate phototransduction, the best-studied phospholipid-mediated signal transduction pathway. Several chapters explore association of gene defects with human retina disease and the generation of animal models of retinal degeneration.