Analytical Techniques In DNA Sequencing

Features

• Cover Type: Hard Cover with 256 pages
• Published by: CRC
• Edition: 1st Edition June 23, 2005
• Written in: English
• ISBN 10 Number: 0824753429
• ISBN 13 Number: 978-0824753429
• Book Dimensions: 9.3 x 6.3 x 0.8 inches
• Weighs: 1 pounds

Product Review
The book includes a short subject and a thorough list of references at the end of each chapter.
—J. Am. Chem. Soc., 2006

The book includes a short subject and a thorough list of references at the end of each chapter.
-J. Am. Chem. Soc., 2006

Product Description
While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding.

Analytical Techniques in DNA Sequencing takes a look at the various DNA sequencing techniques that were developed and put to use during and after the Human Genome Project. Nunnally makes a special effort to trace the development of this branch of research since the early days of radioisotope sequencing. Special attention is paid to the breakthrough Sanger Method (1977), as well as to several other techniques that improved the accuracy, improved the detection limits, and in a variety of ways dramatically reduced the time needed to generate a DNA sequence.

This comprehensive volume describes the improvements in DNA separation based on advanced capillary electrophoresis and microchip sequencing. It also looks at the use ofmass spectrometry and single molecule detection, and takes an in-depth look at the use of various fluorescence methods for the detection of sequencing fragments. One chapter is dedicated to chip-based microfabricated sequencing systems, which could well be the future of DNA sequencing.

The book’s ten chapters, authored by a variety of leading experts in the field, include many of the far-reaching applications of DNA sequencing. Entire chapters are dedicated to DNA typing for forensics, a reevaluation of ancient DNA, and genome analysis.

Reader Reviews
Well the book incledes interesting ideas on new sequencing methods but no way shown on their application. Full of referances and theory...If you are familiar with scientific papers, journals, If you have access of reaching data bases you could find more on them. This book is not suitable for undergraduated or newly graduated students.It is expensive for an easy look up. But if you are interested (deep knowledge required) in organic chemistry and wanted to know the theoritical science beyond new sequencing technologies (not tecniques) you can get one.