Features
- Cover Type: Hard Cover with 656 pages
- Published by: Wiley-Liss
- Edition: 2nd Edition June 3, 2005
- Written in: English
- ISBN 10 Number: 0471474266
- ISBN 13 Number: 978-0471474265
-
Book Dimensions:
11.1 x 8.5 x 1.4 inches
- Weighs: 4 pounds
Product Review
"very readableI would recommend this text to students studying human molecular genetics as well as those involved in their instruction." (American Journal of Medical Genetics, June 15, 2006)
"tailor-made to address[the] need for a textbookmore focused on the nature and characterization of common, classical genetic diseasesan great book that will be applicable to a wide range of students." (
The Quarterly Review of Biology, June 2006)
"An great course book or text to read for updating the established investigator." (
American Journal of Therapeutics, March/April 2006)
"This book would make a worthy addition to any geneticist's library." (
Clinical Chemistry, February 2006)
"The abundance of clearly presented information renders this textbook a chef d'oeuvre." (
New England Journal of Medicine, January 5, 2006)
Product Description
An Introduction to Human Molecular Genetics
Second Edition
Jack J. Pasternak
The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been thoroughly incorporated into the text.
The first part of the text introduces readers to the basics of cytogenetics and Mendelian genetics. Next, techniques and strategies for gene manipulation, mapping, and isolation are examined. Readers will particularly appreciate the text's exceptionally thorough and clear explanation of genetic mapping. The final part features unique coverage of the molecular genetics of distinct biological systems, covering muscle, neurological, eye, cancer, and mitochondrial disorders. Throughout the text, helpful figures and diagrams illustrate and clarify complex material.
Readers familiar with the first edition will recognize the text's same lucid and engaging style, and will find a wealth of new and expanded material that brings them fully up to date with a current understanding of the field, including:
* New chapters on complex genetic disorders, genomic imprinting, and human population genetics
* Expanded and fully revised section on clinical genetics, covering diagnostic testing, molecular screening, and various treatments
This text is targeted at upper-level undergraduate students, graduate students, and medical students. It is also an great reference for researchers and physicians who need a clinically relevant reference for the molecular genetics of inherited human diseases.
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